Optical breast imaging

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This review provides a summary of the current state of optical breast imaging and describes its potential future clinical applications in breast cancer imaging. Optical breast imaging is a novel imaging technique that uses near-infrared light to assess the optical properties of breast tissue. In optical breast imaging, two techniques can be distinguished, i.

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Diffuse optical imaging and spectroscopy of the female breast is an area of active research. We review the present status of this field and discuss the broad range of methodologies and applications. Starting with a brief overview on breast physiology, the remodeling of vasculature and extracellular matrix caused by solid tumors is highlighted that is relevant for contrast in optical imaging.

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Newer types of tests are being developed for breast imaging. Some of these are already being used in certain situations, while others are still being studied. It will take time to see if any are as good as or better than those used today.

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Breast cancer is the most common cancer among women in industrialized countries. At present, X-ray mammography is the gold standard for breast imaging, but has limitations, especially when dense breasts are imaged, as typically occurs in young women. Optical imaging can non-invasively provide information on tissue composition, structure and physiology that can be beneficially exploited for breast lesion detection and identification.

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The present invention relates to medical imaging and, more particularly, to a method and apparatus for breast imaging using non-ionizing photons in the electromagnetic spectrum, such as optical energy. According to the American Cancer Society, inwomen will be diagnosed with breast cancer and 44, women will die from breast cancer. The ACS estimates that 1, women will be diagnosed and more thanwomen will die of breast cancer in the 's.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. We will base our analysis on total hemoglobin contrast which has been shown before by our group to be significantly different between malignant and benign lesions. By setting a threshold total hemoglobin ratio and comparing with the biopsy results, we can obtain a point on the receiver operating characteristic ROC for the selected parameter.

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Dynamic Optical Breast Imaging DOBI is a low cost, non-invasive optical mammographic technique to obtain physiological information on angiogenesis in breast tissue. Angiogenesis reflects the potential aggressiveness of malignant lesions. Slight pressure is applied to the breast 10mmHg and near-infrared light nm from an array of light emitting diodes LED is used to illuminate the breast.

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